Human Chorionic Gonadotropin
Human Chorionic Gonadotropin (HCG) is an ancillary drug not particularly used for the purpose of performance enhancement, but instead is utilized to maintain, increase, or restore proper endogenous Testosterone production.
HCG is a natural analog of luteinizing hormone (LH), the pituitary-produced hormone which stimulates sex hormone production in the testes or ovaries. HCG binds and activates the same receptor as LH and is equally effective in stimulating testosterone production in men, or estrogen production in females.
Male bodybuilders use hCG at the end of an anabolic-androgenic steroid cycle to prevent the breakdown of muscle tissue and to restore the testes to normal abilities. This often returns shrunken testes to their normal size. When used along with a very low-calorie diet, bodybuilders burn off that extra layer of fat over their muscles, giving them an extremely defined look. Females may also use hCG with a very low-calorie diet to burn off unwanted fat.
Human chorionic gonadotropin (HCG) is given as an injection under the skin or into a muscle. Intramuscular or subcutaneous injection of HCG at doses of typically 100-200 IU per day, 200-250 IU every other day, or 250 IU three times per week is effective in supporting testosterone production and testicular size and function where the cause of reduction has been reduced LH production. Doses higher than this provide no further advantage.
When anabolic steroids are used, the body’s pituitary glands go dormant and no longer start producing LH. Without LH, the leydig cells no longer get signaled to produce testosterone anymore, so the user is dependent on exogenous testosterone injections. This is where human chorionic gonadotropin (hcg) comes in. Basically, a gonadotropin is any substance that stimulates the gonads (ovary, testes). With LH being the most important gonadotropin with regards to the male HPTA (hypothalamic–pituitary–gonadal axis). Without LH, your body cannot produce testosterone.
Some bodybuilders use hCG at the end of the steroid dosing cycle to increase testosterone production. Another use for hCG is to take it, via injection, in conjunction with a very low-calorie diet.
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